research, researcher, Nigel, Brockton, colo-rectal, colorectal, breast, colo-rectum,
ACB researcher, Dr. Nigel Brockton
Dr. Nigel Brockton
Research Scientist
Population Health Research
Alberta Health Services - Cancer Care
Tom Baker Cancer Centre
1331-29 Street NW
Calgary, AB T2N 4N2
Email: Nigel.Brockton@albertahealthservices.ca
Current Appointments
|
Research Scientist |
Population Health Research
Alberta Health Services - Cancer Care
Calgary, Alberta |
|
Adjunct Assistant Professor |
Department of Oncology, Faculty of Medicine, University of Calgary
Calgary, Alberta |
| Full Member |
Southern Alberta Cancer Research Institute
Calgary, Alberta |
| Associate Member |
Calgary Institute for Population
and Public Health
Calgary, Alberta |
Education and Training
| 2002-2007 |
PDF |
Division of Maternal and Child Health Sciences
University of Dundee, Dundee
Scotland, UK |
| 1997-2003 |
Ph. D. |
Department of Medicine and Therapeutics
University of Aberdeen, Aberdeen
Scotland, UK |
| 1990-1994 |
B. Sc. (Honours) |
Applied Marine Biology
Heriot-Watt University, Edinburgh Scotland, UK |
Overview of Research Program
Dr. Nigel Brockton is a research scientist who specializes in the field of molecular epidemiology. He believes that there is an inflammatory component to every chronic disease, including cancer. Dr. Brockton has received funding to study breast cancer metastasis to the bone. According to Dr. Brockton, up to 40% of women with breast cancer already have cells from their breast tumours in their bone marrow, but only a small number of those patients actually develop tumours (metastases) in the bone. Dr. Brockton believes this could be related to any number of factors, including vitamin D status and inflammatory factors that encourage the cancer to progress.
Dr Brockton is also working with the Ohlson Research Initiative in head and neck cancer, examining the impact of tumour hypoxia in outcomes in head and neck cancer patients.
Currently Held Research Support
|
Grant Agency |
Project Title |
Investigators |
Total Funding |
Term |
|
AFC |
The Alberta Cohort Study (The Tomorrow Project): Infrastructure Support |
P Robson*
HE Bryant*
CM Friedenreich*
SE McGregor*
I Csizmadi*
K Kopciuk*
N Brockton*
L Kelemen* |
$1,203,262 |
2007-2008 |
| ACRI |
Division of Population Health and Information; Priority Funding Request 2007 |
CM Friedenreich*
K Kopciuk*
L Kelemen*
N Brockton* |
$418,335 |
2008-2011 |
| ACRI |
Breast Cancer to Bone Metastases (B2B) Research Program: A multidisciplinary approach to the investigation of bone metastasis of breast cancer |
N Brockton*
CM Friedenreich*
AM Magliocco
L Cook*
H Vogel
C Shemanko
D Hanley
A Paterson |
$1,390,890 |
2008-2011 |
| ACRI |
HPV, Hypoxia and Head & Neck Cancer |
N Brockton*
Joseph Dort
Harold Lau
Desiree Hao
Anthony Magliocco |
$35,000 |
2008-2009 |
| ACRI |
PHRU Priority Funding Request 2009-2012 |
CM Friedenreich*
SE McGregor*
K Kopciuk*
R Hilsden
L Kelemen*
T Magliocco
N Brockton* |
$3,386,032 |
2009-2012 |
| ACRI |
Breast To Bone (B2B) Metasteses Research Program: Research Equipment Application |
N Brockton*
CM Friedenreich*
A Magliocco |
$10,000 |
2009-2010 |
| TBCC-In House Studies |
Identification of colorectal adenocarcinoma using multiplexed resum proteomic analysi |
O Bathe
D Schriemer
N Brockton* |
$30,065 |
2009-2011 |
| NCI |
Diet, Activity and Lifestyle as a Risk Factor for Colorectal Cancer |
M Slattery*
N Brockton* |
$2,985,359 |
2010-2012 |
|
NIH |
Health Disparities and Breast Cancer |
M Slattery*
G Torres-Mejia
E M John
N Brockton*
L Kelemen* |
$3,710,401 |
2010-2015 |
Salary Awards
|
Grant Agency |
Project Title |
Investigators |
Total Funding |
Term |
| ACRI |
Recruitment & Retention |
N Brockton |
$0 |
2009-2010 |
Conference Funding
|
Grant Agency |
Project Title |
Investigators |
Total Funding |
Term |
| CIHR |
Global Cohorts and Consortia Conference |
LE Kelemen*
NT Brockton* |
$25,000 |
2009 |
Recent Publications (2005-present)
Physical Activity and Postmenopausal Breast Cancer: Proposed Biologic Mechanisms and Areas for Future Research. Heather K. Neilson, Christine M. Friedenreich, Nigel T. Brockton, and Robert C. Millikan. Cancer Epidemiology Biomarkers & Prevention;18(1). January 2009
Systemic folate status and risk of colorectal cancer. Brockton NT. Cancer Causes Control. 2008 Nov, 19(9):1005-1007
Polymorphisms in the methylene tetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake. Sharp L, Little J, Brockton NT, Cotton SC, Masson LF, Haites NE, Cassidy J British Journal of Nutrition. 2008 Feb; 99(2):379-89
Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: A case-control study in the Grampian region of Scotland. Little J, Sharp L, Masson LF, Brockton NT, Cotton SC, Haites NE, Cassidy J. International Journal of Cancer 119 (9): 2155-2164 November 1 2006
Localized depletion: the key to colorectal cancer risk mediated by MTHFR genotype and folate? Brockton NT. Cancer Causes & Control 17 (8): 1005-1016 October 2006.
Glucose production in the human placenta. Leonce J, Brockton N, Robinson S, Venkatesan S, Bannister P, Raman V, Murphy K, Parker K, Pavitt D, Teoh TG, Regan L, Burchell A, Steer P, Johnston DG. Placenta Vol. 27 Suppl A:S103-8 April 2006.
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